Better Living Through Natural Hormone
Replacement
Presented by
Lyn Hanshew, M.D.
June 26, 2005
There
are two major components of a pro-active protocol.
Get the
"good chemistry" in and the "bad chemistry" out.
How?
What's
the "bad" and what's the "good"?
How
much do you have and what do you need?
Accurate
testing is imperative! How do you get it?
"Good
Chemistry"
Micronutrients:
Vitamins, Minerals, Oxygen, H2O, etc.
Macronutrients:
Carbohydrates, Proteins, Fats
Normal
intake should be 50/30/20.
These
are some of the required materials your body needs to make specific
Materials
for specific functions: Hormones, Neurotransmitters, Antibodies,
Enzymes,
Muscles, Nerves, etc.
Labs to
check "good chemistry" levels.
Amino
acids, Minerals, Vitamins Levels, and Fatty Acids Levels.
"Bad
Chemistry"
Chemistry
that impedes or blocks proper functions of the body.
Environmental
toxins : Heavy metals, Mercury amalgam, Pesticides,
Artificial
sweeteners and colorings, Toxins from bacteria, viruses, fungi, etc.
These
toxins significantly negatively affect the Endocrine system,
Immune
system and all other organ systems based upon exposure
and
genetic capability for detoxification.
Chronic
Stress Chemistry: results in high level of Adrenal Hormones, such as,
Cortisol
and eventually suppresses DHEA, Testosterone, Estradiol, Progesterone
and
Thyroid Hormones.
Symptoms
of Toxicity
Fatigue,
Insomnia, Anxiety, Mood Swings,
Decreased
Concentration, Short-term Memory Deficits
Central
Obesity, Decreased Glucose Regulation, High LDL Cholesterol,
Low HDL Cholesterol
Decreased
Digestion, Decreased Adsorption, Constipation
Numbness,
Tingling, Weakness, Cold, Hot Flashes, Skin Rash, Hair Loss
Decreased
Libido, Decreased Sexual Function, Menstrual Abnormalities
Symptoms of Hormone Imbalance
Fatigue,
Insomnia, Anxiety, Mood Swings,
Decreased
Concentration, Short-term Memory Deficits
Central
Obesity, Decreased Glucose Regulation, High LDL Cholesterol,
Low HDL Cholesterol
Decreased
Digestion, Decreased Adsorption, Constipation
Numbness,
Tingling, Weakness, Cold, Hot Flashes, Skin Rash, Hair Loss
Decreased
Libido, Decreased Sexual Function, Menstrual Abnormalities
Testing for Heavy Metals and Other
Toxins
It is
the liver's major job to detoxify the body through 4 pathways.
Heavy
metals are the most destructive. Blood tests are useless
If
Mercury Amalgam is present:
Only
mild detoxification protocols may be used to test and treat.
Oral IV
CaEdta - collect urine
Oral
DMSA - collect stool
Oral
Nutritional Supplementation
And
Somatic Therapies
If NO
Mercury Amalgam is present:
IV
DMPS/CaEdta protocol - collect urine
Accurate Testing is Difficult to Achieve
The
American Academy of Anti-Aging
Medicine recommends that the following hormones
be assessed and the following blood tests be done:
Adrenal
|
Lab Test
|
Code
|
DHEA
Estradiol
Testosterone
Progesterone
Thyroid
Pituitary
Human Growth Hormone
|
DHEA - SO4
Total Estradiol
Total Testosterone
Total Progesterone
Free T3, Free T4
IGF - 1
|
259.9
244.9
259.9
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Recommendations of the American Academy of Anti-Aging Medicine
Test
Optimal Values
Male
Female
DHEA -
SO4 >450 mcg/dl >400 mcg/dl
Estradiol
<50 pg/dl >30 pg/dl
Progesterone
1.0 ng/dl 1.0 ng/dl
Testosterone
>600-1000 ng/dl 30-35 ng/dl
Free T3
4.5-4.9 pg/dl 4.5-4.9 pg/dl
Free T4
1.0 ng/dl 1.0 ng/dl
IGF - 1
>300 ng/ml >300 ng/ml
How Do I Address Any Hormone Deficiency?
A -
Nutritionally support biochemical pathways
B -
Detoxify any blocks in the pathway
C -
Depending on the severity of the symptoms and lab values,
Bio-identical
Hormones can be used to supplement.
Hopefully,
with detoxification and nutritional support,
endogenous
production of hormones will resume.
Nutritional
Support
B -
Complex
B - 12
IM, IV
Mg
citrate 500 mg/day
Ca
citrate 1500 mg/day
Electrolytes,
K, Na, Cl
Vitamin
C - 6-8 g/day, also a detoxifying agent
Omega 3
Fatty Acids, not 6 or 9
Multi-vitamin
with Selenium and Iron
Detoxification protocols
Oral
agents: Fiber- 40-60 g/day
Chlorella
Ambrotose-
contains 8 essential glyconutrients
Vitamin
C- 6-8g/day
DMSA-
weak agent, not effective for Mercury
DMPS-
effective for Mercury, best if used IV or IM
Cilantro
IM
agents: DMPS, best for Mercury
IV
agents: DMPS, best for Mercury
Somatic
treatments- Infrared, Ozone, Steam/Dry Sauna, Cranial-Sacral,
Energetic
Bodywork, Acupuncture, Lymphatic Drainage, Massage, Oxidative Colonic
Therapy, Chiropractic, Electomagnetic Field work
Bio-identical
Hormones
Bio-identical
hormones are genetic identical to human hormones.
Premarin
= Pregnant Mares' Urine and is associated with increased uterine and
breast cancer. 26 different horse estrogens are present in Premarin.
Armour
is pig-derived and made in a ratio of T4 and T3. You cannot independently
adjust the two hormones.
Thyrolar
is cow-derived and made in a ratio of T4 and T3. You cannot
independently
adjust the two hormones.
Bio-identical
hormones are available from your friendly, neighborhood Compounding
Pharmacy and on-line sources, such www.Nanomedhealth.com.
There
are various routes of administration: oral, sublingual, topical,
injectable, patch and suppository.
Hormones
levels can be checked every 4-6 weeks to monitor levels.
If your
levels do not increased, consider changing route as well as dose.
Starting
Doses of Replacement Bio-Identical Hormones Based Upon Labs
In
supplementing hormone deficiencies, start with DHEA, the Mother Precursor
hormone of the adrenal pathways. Strive for optimal levels of DHEA before
addressing other derivative hormones, such as Estradiol, Progesterone and
Testosterone. Do independently supplement, Estradiol, Progesterone and
Testosterone, if the levels are significantly low, as indicated below:
DHEA
(Mother Precursor Hormone)- If less than: 100 mcg/dl, take 25mg/day
(Male
and Female) 200 mcg/dl, take 20 mg/day
300
mcg/dl, take15 mg/day
400
mcg/dl, take 10mg/day
Estradiol-Female:
If less than 20 pg/dl, supplement independently of DHEA.
Start
with 0.5mg.
-Males
rarely require Estradiol supplementation.
Progesterone-
Female: If less than 1.0 ng/dl, with symptoms, such as, menstrual
irregularities, start with 5mg/day supplementation. Again, supplement
DHEA as required for optimal levels.
Testosterone-
Female: If lab level is 20-29ng/dl, start with 0.625mg/day
10-19ng/dl,
start with 1.25mg/day
Male: If lab level is less than 300ng/dl, start with
2.5mg/day
Again, supplement DHEA to optimal levels.
Thyroid Supplementation
Free T3
- Liothyronine (Cytomel) - The active thyroid hormone derived from Free
T4.
Free T4
is converted into Free T3 in the liver and kidney by the 5'deiodinase
enzyme.
This
enzyme is inactivated by the heavy metals, Mercury, Lead and Cadmium.
Liothyronine
- compounded, can be made in any dose required and in a slow-release
form.
Cytomel
is the synthetic form, made in 5, 25, and 50 mcg tablets that can be
dissolved sublingually.
Free T3
- If 3.5-4.0 pg/dl, take 5 mcg 2 X day
2.9-3.4
pg/dl, take 10 mcg 2 X day
2.4-2.8
pg/dl, take 15 mcg 2 X day
1.8-2.3
pg/dl, take 20 mcg 2 X day
<
1.7 pg/dl, take 25 mcg 2 X day
Start
low and slow with thyroid hormone supplementation. You may titrate up the
dose every 3-5 days. Labs can be re-checked every 4 weeks. Blood should
be drawn 2 hours after morning dose.
Free T4
- Levothyroxine-(Synthroid) - This is the inactive hormone produced by
the thyroid gland. It must be converted into the active Free T3 for
proper metabolic function.
Free T4
- If less than 1.0 ng/dl, take 0.05 mg/day
0.05
ng/dl, take 1.0mg/day
Levels
can be re-checked every 4 weeks.
Human
Growth Hormone Replacement
IGF-1 =
<200 ng/ml, take 1-2u/day SQ, may titrate up 1u every 2 months based
upon labs.
IGF-1 =
201-300 ng/ml, can try HGH secretogogues. If no improvement, try 1u HGH.
The End
|